Semax is a synthetic heptapeptide developed at the Institute of Molecular Genetics, Russian Academy of Sciences in the 1980s as a neuroprotective agent for stroke and brain trauma. It mimics the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10) but lacks hormonal activity, instead promoting BDNF synthesis, modulating serotonin/dopamine systems, and enhancing gene expression for vascular/immune repair. Approved in Russia for acute ischemic stroke and cognitive disorders, it remains a leading research tool for nootropic and neuroprotective studies. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation.
Key Scientific
- High-purity Semax (≥ 98% by HPLC/MS, acetate salt form)
- Verified heptapeptide sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for BDNF modulation, ischemia models, and cognitive performance research
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Increases BDNF expression and hippocampal neurogenesis for cognitive enhancement and memory consolidation
- Neuroprotective in focal ischemia models: reduces infarct size by 20-30% via vascular/immune gene upregulation
- Improves stroke recovery: enhances motor function and reduces neurological deficits in clinical trials (n=110)
- Antioxidant effects at low doses; modulates enkephalinase inhibition for stress resilience
- Enhances learning in avoidance tasks and reduces heavy metal toxicity in animal models
- Nasal bioavailability >80%; crosses blood-brain barrier effectively
Why Researchers Choose Nationwide Peptides Semax
- Exact Russian clinical-sequence match for authentic neuroprotective effects
- Highest documented BDNF induction among research suppliers
- Transparent analytical data (HPLC >98%, MS confirmation)
- Trusted by neurology, cognitive science, and pharmacology laboratories
- Competitive research pricing with bulk options

