Vasoactive Intestinal Peptide (VIP) is a 28-amino-acid neuropeptide widely distributed in the central and peripheral nervous systems, acting as a neurotransmitter and hormone. It binds VPAC1/VPAC2 receptors to produce potent vasodilation, smooth muscle relaxation, and secretion stimulation (e.g., intestinal fluid, pancreatic bicarbonate). First isolated in 1970 from porcine intestine, it is a key regulator of circadian rhythms, GI function, and immune modulation. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation, ideal for gastroenterology, neurology, and pulmonary research.
Key Scientific Features
- High-purity VIP (≥ 99% by HPLC/MS, acetate salt form)
- Verified 28-amino-acid sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH₂
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for VPAC receptor signaling, smooth muscle relaxation, and secretion studies
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Potent vasodilator and smooth muscle relaxant — used in pulmonary hypertension and erectile dysfunction models
- Stimulates intestinal/pancreatic secretion and inhibits gastric acid
- Neuroprotective in stroke and Parkinson’s models via anti-apoptotic and anti-inflammatory effects
- Modulates circadian rhythms and immune responses (↓ pro-inflammatory cytokines)
- Potential in IBD, asthma, and neurodegenerative disease research
- Half-life ~2 minutes — ideal for acute signaling studies
Why Researchers Choose Nationwide Peptides VIP
- Exact human sequence used in all major neuroendocrine studies
- Highest documented VPAC receptor potency among research suppliers
- Transparent analytical data (HPLC >99%, MS confirmation)
- Trusted by gastroenterology, neurology, and pulmonary research laboratories
- Competitive research pricing with bulk options
