Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic

Thymosin Alpha-1
Thymosin Alpha-1
$75.00 $106.00Price range: $75.00 through $106.00 Select options

Thymosin Alpha-1

Price range: $75.00 through $106.00

Research-grade Thymosin Alpha-1 (Tα1, Zadaxin®), a synthetic 28-amino-acid thymic peptide (Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH), designed for controlled investigations of T-cell maturation, NK cell activation, dendritic cell function, cytokine balance, and broad-spectrum antiviral/immunomodulatory pathways.

Free shipping on all orders over $200 (US)

  • 99% Purity – Third-Party Tested
  • Fast & Reliable Shipping
Guaranteed Safe Checkout

Thymosin Alpha-1 is the N-terminally acetylated, fully synthetic version of prothymosin α fragment 1–28 originally isolated from thymosin fraction 5 (TF5). It is the only thymic peptide with worldwide regulatory approval (Zadaxin®) — licensed in 35+ countries for hepatitis B/C, vaccine adjuvant, and immune enhancement in sepsis/cancer. FDA orphan drug status for hepatocellular carcinoma and stage IV melanoma. This research-grade lyophilized peptide is produced under strict quality controls and provided with full analytical documentation, making it the gold-standard for immunology, virology, and oncology research.

Key Scientific

  • High-purity Thymosin Alpha-1 (≥ 99% by HPLC/MS, acetate salt form)
  • Verified 28-amino-acid sequence with correct N-terminal acetylation
  • Lyophilized formulation for maximum long-term stability
  • Full Certificate of Analysis (COA) with HPLC, MS, amino acid analysis, and bioactivity (T-cell proliferation assay)
  • Manufactured in GMP-aligned, ISO-compliant facilities
  • Ideal for T-cell/NK activation, TLR signaling, and antiviral immunity studies

Research-Referenced Attributes (Based on scientific literature & clinical trials; not therapeutic claims.)

  • Potent T-cell maturation & Th1 cytokine shift (↑ IL-2, IFN-γ, ↓ IL-10)
  • Enhances NK cell cytotoxicity and dendritic cell antigen presentation
  • FDA-approved (Zadaxin®) as HBV/HCV adjunct — 1.6 mg SC twice weekly → 40–60% sustained virologic response improvement
  • Phase 3 sepsis trial (n=360): 28-day mortality ↓ 9.0% vs. placebo (p=0.062, trending)
  • COVID-19 compassionate use: faster viral clearance and reduced inflammatory markers
  • Valuable in chronic viral infections, cancer immunotherapy, vaccine adjuvant, and critical illness research

Why Researchers Choose Nationwide Peptides Thymosin Alpha-1

  • Exact FDA-approved Zadaxin® sequence with correct N-terminal acetylation
  • Highest documented T-cell & antiviral potency among research suppliers
  • Transparent analytical data (HPLC >99%, MS confirmation of acetylation)
  • Trusted by immunology, virology, and critical care laboratories worldwide
  • Competitive research pricing with bulk options

Storage & Handling

  • Store lyophilized powder at –4 °F (long-term) or 39.2 °F (short-term)
  • Store in a tightly sealed container and protect from light, moisture, air exposure, and elevated temperatures.
  • Reconstitute only with bacteriostatic water or sterile saline (typical concentration 1.6–3.2 mg/mL)
  • Reconstituted solutions stable at 39.2 °F for up to 4 weeks; avoid repeated freeze-thaw cycles
  • Use appropriate PPE and aseptic technique

Peptide Research

COA