Thymosin Alpha-1 is the N-terminally acetylated, fully synthetic version of prothymosin α fragment 1–28 originally isolated from thymosin fraction 5 (TF5). It is the only thymic peptide with worldwide regulatory approval (Zadaxin®) — licensed in 35+ countries for hepatitis B/C, vaccine adjuvant, and immune enhancement in sepsis/cancer. FDA orphan drug status for hepatocellular carcinoma and stage IV melanoma. This research-grade lyophilized peptide is produced under strict quality controls and provided with full analytical documentation, making it the gold-standard for immunology, virology, and oncology research.
Key Scientific
- High-purity Thymosin Alpha-1 (≥ 99% by HPLC/MS, acetate salt form)
- Verified 28-amino-acid sequence with correct N-terminal acetylation
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, amino acid analysis, and bioactivity (T-cell proliferation assay)
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for T-cell/NK activation, TLR signaling, and antiviral immunity studies
Research-Referenced Attributes (Based on scientific literature & clinical trials; not therapeutic claims.)
- Potent T-cell maturation & Th1 cytokine shift (↑ IL-2, IFN-γ, ↓ IL-10)
- Enhances NK cell cytotoxicity and dendritic cell antigen presentation
- FDA-approved (Zadaxin®) as HBV/HCV adjunct — 1.6 mg SC twice weekly → 40–60% sustained virologic response improvement
- Phase 3 sepsis trial (n=360): 28-day mortality ↓ 9.0% vs. placebo (p=0.062, trending)
- COVID-19 compassionate use: faster viral clearance and reduced inflammatory markers
- Valuable in chronic viral infections, cancer immunotherapy, vaccine adjuvant, and critical illness research
Why Researchers Choose Nationwide Peptides Thymosin Alpha-1
- Exact FDA-approved Zadaxin® sequence with correct N-terminal acetylation
- Highest documented T-cell & antiviral potency among research suppliers
- Transparent analytical data (HPLC >99%, MS confirmation of acetylation)
- Trusted by immunology, virology, and critical care laboratories worldwide
- Competitive research pricing with bulk options

