MGF is the C-terminal splice variant of IGF-1 (also called IGF-1Ec) that is uniquely upregulated in muscle tissue following mechanical overload or damage. Unlike systemic IGF-1, MGF remains locally active, recruiting satellite cells, promoting myoblast proliferation, and delaying differentiation to drive repair and hypertrophy. First identified in 1996 by Goldspink’s group, it is considered the primary anabolic signal for exercise-induced muscle growth. This research-grade lyophilized peptide is synthesized under strict quality controls and provided with full analytical documentation, making it the gold-standard for muscle regeneration, satellite cell, and mechano-transduction research.
Key Scientific
- High-purity MGF (≥ 98% by HPLC/MS, acetate salt form)
- Verified 24-amino-acid sequence (human IGF-1Ec isoform)
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for satellite cell activation, local IGF-1 signaling, and muscle damage models
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Rapidly induced (>100-fold) in muscle after stretch or damage — the primary “repair” isoform of IGF-1
- Activates satellite cells and delays differentiation → prolonged proliferation phase for greater hypertrophy
- 20–40% increase in muscle cross-sectional area in rodent overload models
- Neuroprotective in ischemic brain and spinal cord injury via local administration
- Synergistic with full-length IGF-1 or IGF-1 LR3 for enhanced repair outcomes
- Valuable in sarcopenia, muscular dystrophy, sports injury, and neurological regeneration research
Why Researchers Choose Nationwide Peptides MGF
- Exact human IGF-1Ec (MGF) sequence used in original Goldspink studies
- Highest documented satellite cell activation among research suppliers
- Transparent analytical data (HPLC >98%, MS confirmation)
- Trusted by muscle physiology, regenerative medicine, and neurology laboratories
- Competitive research pricing with bulk options
