Melatonin is the primary hormone of the pineal gland, responsible for synchronizing circadian rhythms, promoting sleep onset, and acting as one of nature’s most potent antioxidants. Beyond its well-known role in sleep-wake cycles, it directly scavenges reactive oxygen/nitrogen species (ROS/RNS), upregulates glutathione peroxidase and superoxide dismutase, and modulates mitochondrial bioenergetics. This research-grade crystalline or lyophilized melatonin is produced under strict pharmaceutical standards and provided with full analytical documentation, making it the gold-standard for sleep, aging, oncology, and mitochondrial research.
Key Scientific
- Ultra-high-purity Melatonin (≥ 99.9% by HPLC/UV, pharmaceutical grade)
- Verified structure: N-acetyl-5-methoxytryptamine (C13H16N2O2)
- Crystalline powder or lyophilized formulation for maximum stability
- Full Certificate of Analysis (COA) with HPLC, NMR, mass spectrometry, and endotoxin testing
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for circadian biology, antioxidant capacity, and mitochondrial function studies
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Master regulator of circadian rhythms via MT1/MT2 receptors in the SCN
- Direct free-radical scavenger: 5–15× more effective than glutathione or vitamin E at neutralizing hydroxyl radicals
- Increases mitochondrial membrane potential and ATP production under stress
- Phase 3 oncology trials: 20 mg nightly → reduced cachexia, improved survival, and quality of life in advanced cancer
- Neuroprotective in Alzheimer’s, Parkinson’s, and stroke models via SIRT1 and Nrf2 pathways
- Valuable in sleep disorders, jet lag, shift work, cancer supportive care, and aging research
Why Researchers Choose Nationwide Peptides Melatonin
- Pharmaceutical-grade purity used in major clinical oncology and sleep trials
- Highest documented antioxidant potency among research suppliers
- Transparent analytical data (HPLC >99.9%, NMR confirmation)
- Trusted by circadian biology, oncology, neurology, and aging laboratories worldwide
- Competitive research pricing with bulk options
