Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic

Ipamorelin
Ipamorelin
$50.00 – $77.00Price range: $50.00 through $77.00 Select options
HGH Fragment 176-191 HGH Fragment 176-191 Price range: $63.00 through $72.00
Sermorelin Sermorelin Price range: $86.00 through $110.00

Ipamorelin

Price range: $50.00 through $77.00

Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) is a highly selective, synthetic ghrelin mimetic and one of the  cleanest growth hormone-releasing peptides.

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Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) is a highly selective, synthetic ghrelin mimetic and one of the cleanest growth hormone-releasing peptides (GHRPs) available for research. Unlike earlier GHRP-6 or GHRP-2, Ipamorelin exhibits minimal impact on cortisol, prolactin, or ACTH while producing robust, dose-dependent GH pulses that closely mimic natural physiology. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation, making it ideal for neuroendocrine, metabolic, and aging-related studies.

Key Scientific

  • High-purity Ipamorelin (≥ 98% by HPLC/MS, acetate salt form)
  • Verified pentapeptide sequence with Aib (aminoisobutyric acid) and D-amino acid modifications for stability
  • Lyophilized formulation for maximum long-term stability
  • Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
  • Manufactured in GMP-aligned, ISO-compliant facilities
  • Ideal for pulsatile GH release, IGF-1 pathway, and selective GHS-R1a receptor studies

Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)

  • Potent, selective stimulation of pulsatile GH secretion via GHS-R1a (ghrelin receptor) activation
  • Minimal cortisol, prolactin, ACTH, or hunger side effects compared to GHRP-2/6
  • Sustained IGF-1 elevation with physiological GH pulse mimicry
  • Supports muscle protein synthesis, fat oxidation, and bone density in preclinical models
  • Enhances sleep quality (increased slow-wave sleep) and recovery parameters
  • Synergistic with GHRH analogs (CJC-1295, Mod GRF 1-29) for amplified GH release
  • Valuable in aging, metabolism, cachexia, and neuroendocrine signaling research

Why Researchers Choose Nationwide Peptides Ipamorelin

  • Highest selectivity among GHRPs – cleanest GH pulse profile
  • Consistent potency and solubility batch-to-batch
  • Transparent analytical data (HPLC ≥98%, MS confirmation)
  • Trusted by endocrinology, aging, and performance physiology laboratories
  • Competitive research pricing with bulk/research-grade options

Storage & Handling

  • Store lyophilized powder at –4 °F (long-term) or 39.2 °F (short-term)
  • Store in a tightly sealed container and protect from light, moisture, air exposure, and elevated temperatures.
  • Reconstitute only with bacteriostatic water or sterile saline (typical concentration 2–5 mg/mL).
  • Reconstituted solutions are stableat 39.2 °F for up to 4 weeks; avoid repeated freeze-thaw cycles.
  • Use appropriate PPE and aseptic techniques.

Peptide Research

  • PubMed: Raun et al. (1998) selective GH secretagogue [PMID: 9849822]; Beck et al. (2014) POI trial [PMID: 25331030]; Gobbur et al. (1999) bone growth [PMID: 10373343]; Svensson et al. (2000) PK/PD modeling [PMID: 10496658]
    https://pubmed.ncbi.nlm.nih.gov/9849822/
  • Reviews/Clinical: Knoop et al. (2020) GHS in hypogonadism [PMC:7108996]; ClinicalTrials.gov (2011) POI efficacy [NCT01280344]; Peptides.org (2025) safety overview.
    https://www.clinicaltrials.gov/study/NCT01280344
  • Additional: Huddle Men’s Health (2025) stacking protocols.
  • Well-tolerated in trials (87.5% AE incidence similar to placebo), with rare reports of headache, nausea, injection-site pain, or flushing; no significant cortisol/ACTH rises, but monitor for water retention or fatigue in sensitive models.
    https://pubmed.ncbi.nlm.nih.gov/25331030/
  • Induces robust GH release (up to 7-10x baseline) without elevating cortisol, prolactin, or ACTH, even at high doses; rat studies show increased longitudinal bone growth (tibia length +8-12%) and body weight gain, suggesting potential for sarcopenia or growth retardation models
    https://pubmed.ncbi.nlm.nih.gov/9849822/

COA

SKU: Ipamorelin Category:

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