Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic

IGF-1 LR3
IGF-1 LR3
$69.00 – $156.00Price range: $69.00 through $156.00 Select options
ACE-031 ACE-031 $173.00

IGF-1 LR3

Price range: $69.00 through $156.00

IGF-1 LR3 is a synthetic, recombinant analog of insulin-like growth factor-1 (IGF-1), featuring a 13-amino-acid N-terminal extension and an arginine substitution, designed for controlled investigations of cell proliferation, myogenesis, metabolic signaling, and IGF receptor pathways.

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IGF-1 LR3 is a synthetic, recombinant analog of insulin-like growth factor-1 (IGF-1), featuring a 13-amino-acid N-terminal extension and an arginine substitution at position 3. These modifications reduce binding to IGF-binding proteins (IGFBPs), extending its half-life up to 120 times longer than native IGF-1 while enhancing bioavailability and receptor affinity. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation, ideal for in vitro cell culture, muscle physiology, and metabolic research.

Key Scientific

  • High-purity IGF-1 LR3 (≥ 98% by HPLC/MS, receptor-grade where specified)
  • Verified 83-amino-acid sequence with N-terminal extension (MFPAMPLLSLFVN) and Arg3 substitution
  • Lyophilized formulation for enhanced long-term stability
  • Full Certificate of Analysis (COA) included with every batch (HPLC, MS, amino acid analysis)
  • Manufactured in a controlled, GMP-aligned facility
  • Ideal for cell proliferation, myogenesis, and IGF-1 receptor signaling studies

Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)

  • Promotes cell division, hypertrophy, and differentiation in muscle, bone, and connective tissues
  • Enhances fat metabolism and inhibits myostatin for potential muscle repair models
  • Supports glucose, fatty acid, and amino acid uptake in metabolic and growth studies
  • Extended half-life enables sustained IGF-1R activation and reduced IGFBP interference
  • Valuable in lactation, neuroprotection, and large-scale biopharmaceutical cell culture
  • Reliable batch purity, supporting reproducible outcomes in IGF pathway investigations

Why Researchers Choose Nationwide Peptides

  • Receptor-grade potency for maximal in vitro activity (stronger IGF-1R affinity than media-grade)
  • Consistent N-terminal modification and low IGFBP binding for reliable assays
  • Transparent documentation and third-party analytical reporting
  • Trusted by academic, biotechnology, and endocrinology laboratories

Storage & Handling

  • Store lyophilized at –4°F (long-term) or 39.2°F (short-term); stable at room temp for up to 3 weeks
  • Store in a tightly sealed container and protect from light, moisture, air exposure, and elevated temperatures.
  • Reconstitute only according to institutional laboratory protocols (e.g., sterile water at 100 µg/mL)
  • Reconstituted solutions stable at 39.2°F for 2–7 days; add carrier protein (e.g., 0.1% HSA/BSA) for longer storage below –18°C
  • Handle using appropriate PPE and laboratory equipment; avoid repeated freeze-thaw cycles

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