HMG is a purified preparation of human menopausal gonadotropin extracted from postmenopausal women’s urine or produced recombinantly. It provides balanced follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity in an approximately 1:1 ratio, making it the classic agent for superovulation protocols and fertility research. Originally introduced in the 1960s (Pergonal®), it remains the benchmark for combined FSH + LH stimulation studies. This research-grade lyophilized powder is produced under strict pharmaceutical standards and provided with full analytical documentation.
Key Scientific Features
- High-purity HMG (≥ 98% glycoprotein by SDS-PAGE/HPLC)
- Verified FSH (92 aa) + LH (121 aa) heterodimers with correct glycosylation
- Bioactivity: 100–200 IU/mg FSH and 100–200 IU/mg LH (Steelmann-Pohley & Van Hell assays)
- Full Certificate of Analysis (COA) with HPLC, SDS-PAGE, receptor binding, and in-vivo bioassay
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for ovulation induction, spermatogenesis, and HPG axis research
Research-Referenced Attributes (Based on scientific literature & clinical use; not therapeutic claims.)
- Combined FSH + LH activity → synchronized follicular maturation and ovulation trigger
- Classic agent in IVF/ICSI protocols (75–150 IU daily) — pregnancy rates 25–35% per cycle
- Stimulates Leydig cell testosterone and Sertoli cell function in male hypogonadism models
- Preferred over pure FSH when endogenous LH is low (e.g., hypogonadotropic hypogonadism)
- Half-life ~30–40 hours (longer than pure FSH)
- Valuable in fertility, andrology, puberty induction, and steroidogenesis studies
Why Researchers Choose Nationwide Peptides HMG
- Exact clinical-ratio FSH:LH (1:1) used in all major fertility trials
- Highest documented bioactivity (IU/mg) among research suppliers
- Transparent analytical data (receptor binding + in-vivo ovulation assay)
- Trusted by reproductive endocrinology, fertility, and andrology laboratories worldwide
- Competitive research pricing with bulk options
