HCG is a heterodimeric glycoprotein hormone naturally produced by the placenta during pregnancy. Its β-subunit shares 85% homology with luteinizing hormone (LH) and binds the same LH/CG receptor (LHCGR) on Leydig and theca cells to stimulate testosterone and progesterone synthesis. FDA-approved since the 1960s for fertility treatment, cryptorchidism, and hypogonadism (as Pregnyl®, Novarel®, Ovidrel®), it is the gold-standard research tool for reproductive endocrinology and gonadotropin signaling. This research-grade lyophilized powder (recombinant or urinary-derived) is synthesized/extracted under strict quality controls and provided with full analytical documentation.
Key Scientific
- High-purity HCG (≥ 99% by HPLC/SDS-PAGE, acetate or sodium chloride salt form)
- Verified full α (92 aa) + β (145 aa) heterodimer with correct glycosylation and disulfide bonds
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, SDS-PAGE, bioactivity (Leydig cell testosterone assay), and endotoxin testing
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for LH receptor signaling, steroidogenesis, fertility, and HPG axis research
Research-Referenced Attributes (Based on scientific literature & clinical use; not therapeutic claims.)
- Potent LH receptor agonist → rapid testosterone surge in males and ovulation trigger in females
- Sustained half-life (~24–36 hours) vs. LH (~20 minutes) due to high sialylation
- Diagnostic gold standard for Leydig cell function and hypogonadism classification
- Stimulates spermatogenesis and ovarian steroidogenesis in fertility protocols
- Used in bodybuilding/post-cycle therapy research for HPG axis recovery (off-label)
- Valuable in male/female infertility, cryptorchidism, and gonadotropin deficiency models
Why Researchers Choose Nationwide Peptides HCG
- Exact clinical-sequence match to FDA-approved Pregnyl®/Ovidrel® (recombinant)
- Highest documented bioactivity (IU/mg) among research suppliers
- Transparent analytical data (HPLC/SDS-PAGE + in vitro testosterone assay)
- Trusted by reproductive endocrinology, andrology, and fertility laboratories
- Competitive research pricing with bulk options

