Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by Russian scientist Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It mimics the active core of epithalamin, a natural pineal peptide that regulates melatonin and supports telomere maintenance. In preclinical models, it activates telomerase to lengthen telomeres, potentially extending cellular lifespan and delaying age-related decline. Widely studied in Russia for over 30 years in anti-ageing and oncology research, it remains a leading tool for longevity, pineal gland, and geroprotective studies. This research-grade lyophilised powder is synthesised under strict quality controls and provided with full analytical documentation.
Key Scientific
- High-purity Epithalon (≥ 99% by HPLC/MS, acetate salt form)
- Verified tetrapeptide sequence: Ala-Glu-Asp-Gly (AEDG)
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for telomerase activation, telomere length, and pineal/melatonin research
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Activates telomerase enzyme, elongating telomeres in human somatic cells (up to 33% in fibroblast cultures)
- Extends lifespan in fruit flies, mice, and human cell lines; reduces age-related mortality in rodent models
- Normalizes melatonin production and pineal gland function in aging animals
- Suppresses tumor growth (e.g., colon carcinoma, melanoma) and enhances immune response in preclinical oncology studies
- Reduces oxidative stress and improves metabolic parameters (cholesterol, glucose)
- Valuable in longevity, gerontology, oncology, and circadian rhythm research
Why Researchers Choose Nationwide Peptides Epithalon
- Exact Russian clinical-research sequence (AEDG) used in Khavinson studies
- Highest documented telomerase activation among research suppliers
- Transparent analytical data (HPLC >99%, MS confirmation)
- Trusted by gerontology, oncology, and longevity laboratories worldwide
- Competitive research pricing with bulk options
