CJC-1295 Without DAC (Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂) is the original, non-DAC version of CJC-1295 — a modified growth hormone-releasing hormone (GHRH 1-29) with four key substitutions (D-Ala², Gln⁸, Ala¹⁵, Leu²⁷) that dramatically increase resistance to enzymatic degradation while preserving full GHRH receptor potency. Unlike the long-acting DAC version, it has a short half-life of ~30 minutes, producing clean, natural-like GH pulses without the prolonged elevation that can lead to receptor desensitization. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation, making it the preferred choice for researchers studying true pulsatile GH dynamics.
Key Scientific
- High-purity CJC-1295 Without DAC (≥ 99% by HPLC/MS, acetate salt form)
- Verified 29-amino-acid Mod GRF 1-29 sequence (amidated C-terminus)
- Lyophilized formulation for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for pulsatile GH release, pituitary challenge testing, and short-acting GHRH research
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Produces sharp, natural-like GH pulses (peak within 15–30 min, cleared in 2–3 h) — avoids prolonged elevation and receptor downregulation
- 2–5× more potent than native GHRH due to enzymatic resistance
- Increases IGF-1 in a physiological, feedback-regulated manner
- Synergistic with GHRP peptides (Ipamorelin, GHRP-2/6) for 3–10× amplified GH release
- Preserves negative feedback loops — no suppression of endogenous GH axis
- Valuable in aging, muscle physiology, diagnostic testing, and combination secretagogue research
Why Researchers Choose Nationwide Peptides CJC-1295 Without DAC
- Exact clinical-sequence match to original Mod GRF 1-29 (no DAC, amidated)
- Highest purity (>99%) and most accurate pulsatile profile among research suppliers
- Transparent analytical data (HPLC/MS COA, endotoxin-free)
- Trusted by endocrinology, aging, and performance physiology laboratories
- Competitive research pricing with bulk options
