Glutathione (GSH) is the most abundant non-protein thiol in mammalian cells and the primary endogenous antioxidant. This reduced γ-linked tripeptide (L-γ-glutamyl-L-cysteinyl-glycine) directly neutralizes reactive oxygen/nitrogen species, regenerates vitamins C/E, and serves as cofactor for glutathione peroxidase (GPx) and glutathione-S-transferase (GST). Levels decline with age, oxidative stress, and chronic disease, making exogenous supplementation a key tool in redox biology. This research-grade lyophilized powder is produced under strict pharmaceutical standards and provided with full analytical documentation, ideal for oxidative stress, aging, neuroprotection, and detoxification research.
Key Scientific
- Ultra-high-purity reduced Glutathione (≥ 99.5% by HPLC, pharmaceutical grade)
- Verified structure: γ-Glu-Cys-Gly (reduced thiol form, >98% GSH vs. GSSG)
- Lyophilized powder for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, Ellman’s assay (free thiol), mass spectrometry, and endotoxin testing
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for ROS scavenging, GPx/GST cofactor, and redox balance studies
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Most potent endogenous antioxidant: neutralizes ·OH, ONOO⁻, H₂O₂ at near-diffusion-limited rates
- Master regulator of cellular redox state (GSH/GSSG ratio) — critical for protein folding, DNA synthesis, and immune function
- Depletion predicts mortality in critical illness (ICU studies); restoration improves outcomes in sepsis, ARDS, and chemotherapy toxicity
- Neuroprotective in Parkinson’s, Alzheimer’s, and stroke models via Nrf2 activation and mitochondrial preservation
- Essential cofactor for glyoxalase system (methylglyoxal detoxification) and heavy-metal chelation
- Valuable in aging, oncology, critical care, neurology, and environmental toxicology research
Why Researchers Choose Nationwide Peptides Glutathione
- Pharmaceutical-grade reduced GSH used in clinical IV formulations (e.g., TAD 600)
- Highest documented free-thiol content and lowest GSSG contamination among suppliers
- Transparent analytical data (HPLC >99.5%, Ellman’s assay >98% reduced)
- Trusted by redox biology, critical care, and aging laboratories worldwide
- Competitive research pricing with bulk options
