For Research Use Only. Not for human use.
SLU-PP-332 is a non-peptide synthetic small molecule pan-ERR agonist (CAS 303760-60-3) developed by researchers at Saint Louis University. Chemically identified as (E)-4-Hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide, it acts as a potent agonist of estrogen-related receptors ERRα, ERRβ, and ERRγ, with EC₅₀ values of 98 nM, 230 nM, and 430 nM, respectively, without affecting classical estrogen receptors. According to wikipedia.org and tocris.com, SLU-PP-332 has been studied in preclinical mouse models for its effects on ERR-mediated transcriptional programs associated with aerobic metabolism. This research-grade crystalline compound is produced under strict quality controls and is provided with full analytical documentation for use in laboratory research settings only.
Key Scientific Specifications
- High-purity SLU-PP-332 (≥99% by HPLC/MS, free base or salt form)
- Verified structure: (E)-4-Hydroxy-N′-(naphthalen-2-ylmethylene)benzohydrazide
- Molecular formula: C₁₈H₁₄N₂O₂ | Molecular weight: 290.32 g/mol
- Crystalline powder for excellent stability
- Full Certificate of Analysis (COA) with HPLC, MS, NMR, and ERR activation assay (EC₅₀ confirmation)
- Manufactured in GMP-aligned, ISO-compliant facilities
- Suitable for in vitro AMPK/PGC-1α pathway studies and mitochondrial function research
Research-Referenced Attributes (Based on published scientific literature; not intended as therapeutic claims. For research use only.)
- Potent pan-ERR agonist (EC₅₀ 98 nM ERRα, 230 nM ERRβ, 430 nM ERRγ) as documented by tocris.com
- Studied in preclinical mouse models for effects on energy expenditure and fatty acid oxidation pathways
- Investigated for effects on mitochondrial respiration and biogenesis in skeletal muscle cell models in vitro
- Subject of published preclinical research into ERR agonism and metabolic pathway modulation, as reviewed at sciencedirect.com
- No estrogenic receptor activity reported in preclinical studies
Why Researchers Choose SLU-PP-332 From Us
- Consistent with compound specifications used in landmark published ERR agonist studies
- Transparent analytical data (HPLC ≥99%, NMR confirmation)
- Trusted by exercise physiology, metabolism, and mitochondrial research laboratories
- Competitive research pricing with bulk options
This product is strictly for laboratory and research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.
