GHRP-6 is one of the first synthetic ghrelin mimetics developed in the 1980s by Merck Research Laboratories, acting as a potent agonist at the growth hormone secretagogue receptor (GHS-R1a) to stimulate GH release from the pituitary. Unlike GHRH, it operates independently via PKC and Ca²⁺ signaling, with additional effects on appetite and cardio protection. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation, ideal for neuroendocrine, metabolic, and cardioprotective research.
Key Scientific
- High-purity GHRP-6 (≥ 98% by HPLC/MS, acetate salt form)
- Verified hexapeptide sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
- Lyophilized formulation for enhanced long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for GH secretion, PI second messenger, and cytoprotection studies
Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)
- Potent stimulation of GH release via PI turnover and PKC/Ca²⁺pathways in somatotrophs
- Cardioprotective effects, reducing myocardial necrosis and oxidant damage in infarction models
- Oral bioavailability (up to 1% of IV potency) with activity in rats, dogs, and primates
- Appetite induction and weight gain modulation, dependent on insulin/glucose status
- Synergistic with GHRH for amplified GH responses; potential in hypothyroidism and hypercortisolism models
- Cytoprotective roles in preventing multiple organ failure and enhancing cell migration/proliferation
Why Researchers Choose Nationwide Peptides GHRP-6
- Exact Merck-sequence match for authentic GHS-R1a agonism
- Consistent potency and solubility batch-to-batch
- Transparent analytical data (HPLC ≥98%, MS confirmation)
- Trusted by endocrinology, cardiology, and metabolic laboratories
- Competitive research pricing with bulk options
