Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic

AOD9604

$66.00 Buy Now

AOD9604

$66.00

Research-grade AOD9604 is a 16-amino-acid synthetic fragment (Tyr-hGH177-191) of the C-terminal lipolytic domain of human growth hormone (hGH).

AOD9604 is a modified, orally active analogue of the hGH C-terminal fragment (residues 177-191 with N-terminal tyrosine addition and disulfide cyclisation), first developed in the 1990s by Metabolic Pharmaceuticals for obesity treatment. It selectively stimulates lipolysis via upregulation of beta-3 adrenergic receptors without elevating IGF-1 or causing hGH-like anabolic side effects. Despite promising early rodent data, clinical trials showed modest efficacy (1.8 kg additional loss over 12 weeks), leading to development termination in 2007. This research-grade lyophilized powder is synthesized under strict quality controls and provided with full analytical documentation, ideal for metabolic, obesity, and cartilage repair studies.

Key Scientific

High-purity AOD9604 (≥ 98% by HPLC/MS, cyclized acetate salt form)
Verified 16-amino-acid sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe (disulfide bridge between Cys7-Cys14)
Lyophilized formulation for enhanced long-term stability
Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis
Manufactured in GMP-aligned, ISO-compliant facilities
Ideal for lipolytic assays, beta-3 AR modulation, and osteoarthritis research

Research-Referenced Attributes (Based on scientific literature; not intended as therapeutic claims.)

Stimulates lipolysis and fat oxidation via beta-3 adrenergic receptor upregulation in adipose tissue
Reduces body weight and improves lipid profiles in obese rodent models without IGF-1 elevation
Potential cartilage repair and osteoporosis prevention through direct osteoblast stimulation
No genotoxic, mutagenic, or diabetogenic effects observed in preclinical safety studies
Oral bioavailability in animal models; well-absorbed with rapid degradation kinetics
Valuable in metabolic syndrome, NAFLD, and performance enhancement research

Why Researchers Choose Nationwide Peptides AOD9604

Exact clinical-sequence match with tyrosine addition and disulfide cyclization
Consistent potency and oral activity batch-to-batch
Transparent analytical data (HPLC >98%, MS confirmation)
Trusted by metabolic endocrinology, obesity, and orthopedics laboratories
Competitive research pricing with bulk options

Storage & Handling

Store lyophilized powder at –4 °F (long-term) or 39.2 °F (short-term)
Store in a tightly sealed container and protect from light, moisture, air exposure, and elevated temperatures.
Reconstitute only with bacteriostatic water or sterile saline (typical concentration 2–5 mg/mL)
Reconstituted solutions stable at 39.2 °F for up to 4 weeks; avoid repeated freeze-thaw cycles
Use appropriate PPE and aseptic technique