Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic
GHK-Cu
GHK-Cu
$53.00 – $70.00Price range: $53.00 through $70.00
GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) first isolated from human plasma designed for controlled investigations of extracellular matrix remodeling, collagen/elastin synthesis, wound-healing pathways, antioxidant responses, and copper-dependent signaling in cellular and tissue models.
GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) first isolated from human plasma in 1973. When complexed with copper (II) at a 1:1 ratio, it exhibits potent regenerative and protective actions in preclinical models, making it one of the most widely studied peptides in skin biology, wound healing, and anti-aging research. This research-grade lyophilized formulation is synthesized under strict quality controls and provided with full analytical documentation.
Key Scientific
- High-purity GHK-Cu (≥ 98% by HPLC, copper-bound form)
- Accurate 1:1 copper-peptide stoichiometry verified by mass spectrometry
- Lyophilized powder for maximum long-term stability
- Full Certificate of Analysis (COA) with HPLC, MS, and copper content
- Manufactured in GMP-aligned, ISO-compliant facilities
- Ideal for dermatological, regenerative medicine, and copper-signaling research
Research-Referenced Applications (Based on scientific literature; not therapeutic claims)
- Stimulation of collagen I, III, VII, elastin, and glycosaminoglycan synthesis
- Acceleration of wound contraction and re-epithelialization in animal models
- Modulation of MMP/TIMP balance and fibroblast activity
- Antioxidant and anti-inflammatory effects via SOD-like activity and cytokine regulation
- Support of angiogenesis and nerve outgrowth in tissue-repair studies
- Epigenetic regulation (resetting of gene expression patterns in aging cells)
- Copper homeostasis and cellular protection against oxidative stress
Why Researchers Choose Nationwide Peptides GHK-Cu
- Verified copper-peptide complex (not free GHK + copper salt)
- Consistent blue color and solubility profile batch-to-batch
- Transparent analytical data (HPLC, MS, AAS for copper)
- Trusted by dermatology, tissue-engineering, and cosmetic-science laboratories
- Competitive research pricing with bulk options
Storage & Handling
- Store lyophilized powder at –4 °F (long-term) or 39.2 °F (short-term).
- Store in a tightly sealed container and protect from light, moisture, air exposure, and elevated temperatures.
- Reconstitute only with sterile laboratory buffers (e.g., saline, DMSO < 5%, or acetic acid solutions).
- Reconstituted solutions are stable at 39.2 °F for up to 4 weeks; avoid repeated freeze-thaw cycles.
- Use appropriate PPE and aseptic technique.
Peptide Research
- ubMed/PMC: Pickart (2012) on oxidative stress/neuroprotection [PMID: 23723666]; Pickart et al. (2018) on gene data/regeneration [PMID: 30018507]; Pickart (2008) tissue remodeling [PMID: 18644186]; Pickart et al. (2017) nervous system [PMID: 28208804] – https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/
- Reviews: Bagno et al. (2020) skin regeneration [PMID: 26177688]; Pickart et al. (2015) COPD reversal [PMID: 26177688]; Seyhan et al. (2024) anti-wrinkle permeability [PMID: 39963574]. – https://pmc.ncbi.nlm.nih.gov/articles/PMC8789089/
- Recent: Innerbody (2025) benefits/side effects; Peptides.org (2025) safety profile; PMC reviews on gene data [PMC6073405, PMC8789089]
- Reviews/Trials: Ogórek et al. (2025) skin permeation [PMID: 40586182]; Liu et al. (2023) microemulsions [PMID: 37896231]; Saraceno et al. (2021) cancer gene modulation [DOI: 10.21926/obm.genet.2102128] – https://pubmed.ncbi.nlm.nih.gov/11045606/
COA
